The bHLH transcription factor E protein negatively regulates endoreplication in the salivary gland cells
Background: Endoreplication is a variant cell cycle which generates massive DNA replication with no features of mitosis.In addition to abnormal occurrence of endoreplication in cancer cells, it is often Shoes found in plants and many different animal organs, such as liver, placenta, and Drosophila larval tissues.In treatment with anti-mitotic drugs